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Download e-book for kindle: ADME-Enabling Technologies in Drug Design and Development by Donglu Zhang,Sekhar Surapaneni

By Donglu Zhang,Sekhar Surapaneni

ISBN-10: 0470542780

ISBN-13: 9780470542781

A complete consultant to state of the art instruments in ADME research

The final decade has noticeable great growth within the improvement of analytical recommendations corresponding to mass spectrometry and molecular biology instruments, leading to vital advances in drug discovery, relatively within the region of absorption, distribution, metabolism, and excretion (ADME).

ADME-Enabling applied sciences in Drug layout and improvement makes a speciality of the present cutting-edge within the box, proposing a finished overview of the newest instruments for producing ADME info in drug discovery. It examines the broadest attainable variety of obtainable applied sciences, giving readers the knowledge they should pick out the appropriate software for a given program, a key needful for acquiring favorable ends up in a well timed style for regulatory filings. With over thirty contributed chapters through a global workforce of specialists, the ebook provides:

  • A thorough exam of present instruments, protecting either electronic/mechanical applied sciences and biologically dependent ones

  • Coverage of purposes for every expertise, together with key parameters, optimum stipulations for meant effects, protocols, and case studies

  • Detailed dialogue of rising instruments and strategies, from stem cells and genetically changed animal versions to imaging technologies

  • Numerous figures and diagrams during the text

Scientists and researchers in drug metabolism, pharmacology, medicinal chemistry, pharmaceutics, toxicology, and bioanalytical technology will locate ADME-Enabling applied sciences in Drug layout and improvement a useful advisor to the full drug improvement method, from discovery to regulatory issues.

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ADME-Enabling Technologies in Drug Design and Development by Donglu Zhang,Sekhar Surapaneni

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